Basic Information
ID: ALA4820516
Type: ADME
Description: Drug metabolism in dog liver microsomes assessed as 5-(5-(4-Hydroxyphenyl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-7-yl)-3-(trifluoromethyl)picolinonitrile metabolite formation at 10 uM incubated for 60 mins in presence of glutathione and NADPH by LC-MS/MS analysis
Organism: Canis lupus familiaris
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4820516
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 502.52 | 3.56 | 3.56 |
| 501.53 | 4.16 | 4.16 |