Basic Information
ID: ALA4820536
Type: Functional
Description: Anti-osteoporosis activity in C57BL/6 mouse BMM cells assessed as inhibition of M-CSF/RANKL-induced osteoclastogenesis by measuring reduction in multinucleated TRAP+ cells incubated for 5 days with media replenishment for every 48 hrs measured by TRAP-staining based analysis
Organism: Mus musculus
Strain: C57BL/6
Cell type: BMMC
Activity Charts
Bioactivity
Activity Types for Assay ALA4820536
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 271.08 | -1.27 | -1.27 |
| 368.47 | 1.48 | 1.48 |
| 350.46 | 1.96 | 1.96 |
| 352.47 | 2.04 | 2.04 |
| 332.44 | 2.77 | 2.77 |
| 332.44 | 3.12 | 3.12 |
| 266.38 | 2.32 | 2.32 |
| 465.59 | 4.10 | 4.10 |
| 446.59 | 4.44 | 4.44 |
| 427.61 | 4.63 | 4.63 |
| 411.54 | 4.16 | 4.16 |
| 460.62 | 4.82 | 4.82 |
| 451.61 | 4.57 | 4.57 |
| 465.63 | 4.62 | 4.62 |
| 455.62 | 4.20 | 4.20 |
| 439.57 | 4.70 | 4.70 |
| 421.58 | 4.57 | 4.57 |
| 453.60 | 4.75 | 4.75 |
| 456.03 | 5.22 | 5.22 |
| 451.61 | 4.57 | 4.57 |
| 435.56 | 4.09 | 4.09 |
| 422.57 | 3.96 | 3.96 |
| 514.46 | 4.85 | 4.85 |
| 428.60 | 4.02 | 4.02 |
| 500.48 | 5.33 | 5.33 |
| 467.58 | 4.27 | 4.27 |
| 435.61 | 4.87 | 4.87 |
| 465.63 | 4.62 | 4.62 |
| 449.59 | 4.13 | 4.13 |
| 453.58 | 3.98 | 3.98 |
| 466.58 | 4.47 | 4.47 |
| 481.63 | 4.58 | 4.58 |
| 435.61 | 4.61 | 4.61 |
| 479.62 | 4.14 | 4.14 |
| 503.61 | 5.63 | 5.63 |
| 441.64 | 4.67 | 4.67 |
| 449.64 | 4.92 | 4.92 |