Basic Information
ID: ALA4820882
Type: Binding
Description: Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response incubated for 30 mins by fluorescence-based FLIPR membrane potential blue assay
Organism: Homo sapiens
Cell type: tsA201
Activity Charts
Bioactivity
Activity Types for Assay ALA4820882
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 334.42 | 2.09 | 2.09 |
| 965.16 | 4.04 | 4.04 |
| 865.09 | 6.20 | 6.20 |
| 532.69 | 3.51 | 3.51 |
| 658.93 | 7.02 | 7.02 |
| 893.14 | 6.98 | 6.98 |
| 951.14 | 3.65 | 3.65 |
| 1676.15 | ||
| 1147.52 | ||
| 937.11 | 3.26 | 3.26 |
| 837.03 | 5.42 | 5.42 |
| 1400.00 | ||
| 1315.84 | ||
| 1103.40 | ||
| 1035.30 | ||
| 1507.83 | ||
| 780.93 | 3.86 | 3.86 |
| 921.20 | 7.76 | 7.76 |
| 1063.35 | ||
| 1007.25 | ||
| 475.63 | 4.39 | 4.39 |
| 979.19 | 4.43 | 4.43 |
| 808.98 | 4.64 | 4.64 |
| 794.95 | 4.25 | 4.25 |
| 1203.62 | ||
| 1019.24 | ||
| 1259.73 |