ID: ALA4820958
Type: ADME
Description: Antagonist activity at human AM1 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 30 mins followed by forskolin addition in presence of IBMX and measured after 15 mins by TR-FRET assay
Organism: Homo sapiens
Cell type: CHO-K1
Bioactivity
Activity Types for Assay ALA4820958
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
511.63 | 3.54 | 3.54 |
525.65 | 4.10 | 4.10 |
562.67 | 4.33 | 4.33 |
483.57 | 3.48 | 3.48 |
551.69 | 4.34 | 4.34 |
511.63 | 3.54 | 3.54 |
525.65 | 4.10 | 4.10 |
537.66 | 3.73 | 3.73 |
525.65 | 3.80 | 3.80 |
512.61 | 3.58 | 3.58 |
507.59 | 3.96 | 3.96 |
512.61 | 2.94 | 2.94 |
551.69 | 4.16 | 4.16 |
522.61 | 3.96 | 3.96 |
548.65 | 4.27 | 4.27 |
497.60 | 3.67 | 3.67 |
553.67 | 3.07 | 3.07 |
581.72 | 3.92 | 3.92 |
559.67 | 5.15 | 5.15 |
503.65 | 3.23 | 3.23 |
525.61 | 3.18 | 3.18 |
551.69 | 4.29 | 4.29 |
489.60 | 3.54 | 3.54 |
525.65 | 3.58 | 3.58 |