Basic Information
ID: ALA4820959
Type: Binding
Description: Antagonist activity at human CGRP-2 (8 to 37 residues) expressed in 1321N1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 30 mins followed by forskolin addition in presence of IBMX and measured after 15 mins by TR-FRET assay
Organism: Homo sapiens
Cell type: 1321N1
Activity Charts
Bioactivity
Activity Types for Assay ALA4820959
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 511.63 | 3.54 | 3.54 |
| 525.65 | 4.10 | 4.10 |
| 562.67 | 4.33 | 4.33 |
| 483.57 | 3.48 | 3.48 |
| 551.69 | 4.34 | 4.34 |
| 511.63 | 3.54 | 3.54 |
| 525.65 | 4.10 | 4.10 |
| 537.66 | 3.73 | 3.73 |
| 525.65 | 3.80 | 3.80 |
| 512.61 | 3.58 | 3.58 |
| 507.59 | 3.96 | 3.96 |
| 512.61 | 2.94 | 2.94 |
| 551.69 | 4.16 | 4.16 |
| 522.61 | 3.96 | 3.96 |
| 548.65 | 4.27 | 4.27 |
| 497.60 | 3.67 | 3.67 |
| 553.67 | 3.07 | 3.07 |
| 581.72 | 3.92 | 3.92 |
| 559.67 | 5.15 | 5.15 |
| 503.65 | 3.23 | 3.23 |
| 525.61 | 3.18 | 3.18 |
| 551.69 | 4.29 | 4.29 |
| 489.60 | 3.54 | 3.54 |
| 525.65 | 3.58 | 3.58 |