Basic Information
ID: ALA4821049
Type: Binding
Description: Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uM
Format: BAO_0000219
Organism: Homo sapiens
Cell type: A498
Target: DNA topoisomerase II alpha(ALA1806)
Document: ALA4819046
Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uM: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4821049
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 543.53 | 0.00 | 0.00 |
| 567.87 | 8.70 | 8.70 |
| 533.97 | 7.85 | 7.85 |
| 384.35 | 3.12 | 3.12 |
| 372.40 | 4.23 | 4.23 |
| 557.86 | 9.25 | 9.25 |
| 367.36 | 3.56 | 3.56 |
| 355.35 | 3.49 | 3.49 |