Basic Information
ID: ALA4821190
Type: Binding
Description: Agonist activity at human GABAB expressed in HEK293T cells co-transfected with human CaV2.2-alpha1B channel assessed as inhibition of CaV2.2-mediated Ba2+ peak-current amplitude at 100 nM at -80 to 10 mV holding potential after 72 hrs by whole cell patch clamp assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293T
Target: GABA-B receptor(ALA2111463)
Document: ALA4819053
Agonist activity at human GABAB expressed in HEK293T cells co-transfected with human CaV2.2-alpha1B channel assessed as inhibition of CaV2.2-mediated Ba2+ peak-current amplitude at 100 nM at -80 to 10 mV holding potential after 72 hrs by whole cell patch clamp assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4821190
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1766.90 | ||
| 1807.01 | ||
| 1770.93 |