Basic Information
ID: ALA4821487
Type: Binding
Description: Inhibition of N-terminal GST-tagged and C-terminal His-tagged human HDAC4 (627 to 1084 residues) expressed in baculovirus infected Sf9 cells using Boc Lys(TFA)-AMC as substrate preincubated for 5 mins followed by substrate addition and further incubated for 30 mins by fluorogenic assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4821487
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 348.43 | 4.61 | 4.61 |
| 416.42 | 5.63 | 5.63 |
| 364.43 | 3.62 | 3.62 |
| 382.87 | 5.26 | 5.26 |
| 378.45 | 4.62 | 4.62 |
| 408.26 | 5.01 | 5.01 |
| 421.48 | 3.82 | 3.82 |
| 407.45 | 2.72 | 2.72 |
| 468.54 | 5.26 | 5.26 |
| 394.45 | 3.63 | 3.63 |
| 417.49 | 4.11 | 4.11 |
| 482.57 | 5.56 | 5.56 |
| 391.45 | 3.71 | 3.71 |
| 410.52 | 4.35 | 4.35 |
| 398.87 | 4.28 | 4.28 |
| 547.43 | 6.02 | 6.02 |
| 432.42 | 4.64 | 4.64 |
| 394.52 | 5.33 | 5.33 |
| 405.48 | 4.81 | 4.81 |