Basic Information
ID: ALA4821564
Type: Binding
Description: Inhibition of N-terminal GST-fused human recombinant full length SYK (1 to 635 residues) expressed in baculovirus-infected Sf21 cells using FAM-22 peptide as substrate at 1 uM preincubated with enzyme for 10 mins followed by substrate addition for 30 mins in presence of ATP by caliper mobility shift assay relative to control
Organism: Homo sapiens
Cell type: Sf21
Activity Charts
Bioactivity
Activity Types for Assay ALA4821564
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 466.54 | 4.35 | 4.35 |
| 562.08 | 3.50 | 3.50 |
| 479.54 | 2.43 | 2.43 |
| 548.05 | 3.11 | 3.11 |
| 501.55 | 3.00 | 3.00 |
| 489.54 | 3.55 | 3.55 |
| 485.50 | 2.77 | 2.77 |
| 501.55 | 3.37 | 3.37 |
| 492.97 | 3.43 | 3.43 |
| 487.52 | 3.33 | 3.33 |
| 479.54 | 2.43 | 2.43 |
| 544.62 | 3.26 | 3.26 |
| 439.48 | 1.69 | 1.69 |
| 501.55 | 3.37 | 3.37 |
| 465.51 | 2.04 | 2.04 |
| 501.55 | 3.00 | 3.00 |
| 509.95 | 3.38 | 3.38 |
| 509.95 | 3.38 | 3.38 |
| 487.52 | 3.33 | 3.33 |
| 499.53 | 3.16 | 3.16 |
| 535.01 | 3.20 | 3.20 |
| 501.55 | 3.72 | 3.72 |