Activation of human NAMPT assessed as increase in NMN production at 100 uM by fluorescence based analysis relative to 30 uM ethyl 4-(3-(pyridin-4-ylme...

Basic Information

ID: ALA4822018

Type: Binding

Description: Activation of human NAMPT assessed as increase in NMN production at 100 uM by fluorescence based analysis relative to 30 uM ethyl 4-(3-(pyridin-4-ylmethyl)ureido)benzoate

Format: BAO_0000357

Organism: Homo sapiens

Target: Nicotinamide phosphoribosyltransferase(ALA1744525)

Document: ALA4819093

Activation of human NAMPT assessed as increase in NMN production at 100 uM by fluorescence based analysis relative to 30 uM ethyl 4-(3-(pyridin-4-ylmethyl)ureido)benzoate: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4822018

Emax

Total(19)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
299.33	2.58	2.58
451.53	3.56	3.56
343.39	3.74	3.74
343.39	3.72	3.72
334.34	2.71	2.71
428.37	4.01	4.01
344.38	3.11	3.11
376.42	2.89	2.89
386.46	3.91	3.91
348.37	1.85	1.85
342.40	4.55	4.55
347.38	2.45	2.45
384.44	4.35	4.35
428.37	4.01	4.01
392.42	1.96	1.96
387.48	4.79	4.79
333.36	2.44	2.44
372.47	4.27	4.27
310.36	2.57	2.57