Basic Information
ID: ALA4822097
Type: Binding
Description: Potency index, ratio of diclofenac sodium IC50 to test compound IC50 for human recombinant COX-2 using arachidonic acid as substrate preincubated with enzyme for 5 mins followed by substrate addition by colorimetric analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: Cyclooxygenase-2(ALA230)
Document: ALA4819098
Potency index, ratio of diclofenac sodium IC50 to test compound IC50 for human recombinant COX-2 using arachidonic acid as substrate preincubated with enzyme for 5 mins followed by substrate addition by colorimetric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4822097
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 389.44 | 3.03 | 3.03 |
| 604.09 | 5.58 | 5.58 |
| 419.47 | 3.04 | 3.04 |
| 509.54 | 3.06 | 3.06 |
| 403.47 | 3.34 | 3.34 |
| 419.47 | 3.04 | 3.04 |
| 409.50 | 3.40 | 3.40 |
| 447.52 | 3.81 | 3.81 |
| 495.56 | 4.61 | 4.61 |
| 509.54 | 3.06 | 3.06 |
| 493.55 | 3.36 | 3.36 |
| 395.47 | 3.09 | 3.09 |
| 511.99 | 4.31 | 4.31 |
| 449.49 | 3.05 | 3.05 |