Basic Information
ID: ALA4822105
Type: Functional
Description: Potency index, ratio of celecoxib IC50 to test compound IC50 for inhibition of LPS-induced IL-6 production in mouse RAW264.7 cells preincubated for 2 hrs followed by LPS stimulation and measured after 20 hrs by ELISA
Format: BAO_0000219
Organism: Mus musculus
Cell type: RAW264.7
Target: RAW264.7(ALA612557)
Document: ALA4819098
Potency index, ratio of celecoxib IC50 to test compound IC50 for inhibition of LPS-induced IL-6 production in mouse RAW264.7 cells preincubated for 2 hrs followed by LPS stimulation and measured after 20 hrs by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4822105
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 604.09 | 5.58 | 5.58 |
| 419.47 | 3.04 | 3.04 |
| 419.47 | 3.04 | 3.04 |
| 495.56 | 4.61 | 4.61 |
| 509.54 | 3.06 | 3.06 |
| 511.99 | 4.31 | 4.31 |