Basic Information
ID: ALA4822135
Type: Binding
Description: Binding affinity to Cereblon in human Flp293T cells transfected with BRD4(BD2)-GFP fusion protein and mCherry reporter assessed as inhibition of dBET6-induced BRD4(BD2) degradation after 5 hrs fluorescence based analysis
Organism: Homo sapiens
Cell type: Flp-In-293
Activity Charts
Bioactivity
Activity Types for Assay ALA4822135
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 770.83 | 5.61 | 5.61 |
| 663.76 | 4.67 | 4.67 |
| 800.68 | 4.17 | 4.17 |
| 893.72 | 4.16 | 4.16 |