Basic Information
ID: ALA4822200
Type: Binding
Description: Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc level incubated for 2 hrs by ELISA
Format: BAO_0000019
Organism: Homo sapiens
Target: Methylcytosine dioxygenase TET2(ALA4523344)
Document: ALA4819102
Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc level incubated for 2 hrs by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4822200
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 147.09 | -1.73 | -1.73 |
| 144.08 | -0.72 | -0.72 |
| 160.12 | -0.54 | -0.54 |
| 174.15 | -0.15 | -0.15 |
| 228.12 | 0.40 | 0.40 |
| 160.12 | -0.54 | -0.54 |
| 148.11 | -0.70 | -0.70 |
| 160.12 | -0.54 | -0.54 |