Basic Information
ID: ALA4822225
Type: Binding
Description: Inhibition of human His-tagged PERK expressed in Escherichia coli assessed as eIF2alpha phosphorylation by TR-FRET assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Eukaryotic translation initiation factor 2-alpha kinase 3(ALA6030)
Document: ALA4819104
Inhibition of human His-tagged PERK expressed in Escherichia coli assessed as eIF2alpha phosphorylation by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4822225
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.45 | 3.42 | 3.42 |
| 474.90 | 4.07 | 4.07 |
| 427.41 | 2.34 | 2.34 |
| 432.52 | 3.62 | 3.62 |
| 453.49 | 4.45 | 4.45 |
| 458.44 | 3.56 | 3.56 |
| 454.48 | 3.73 | 3.73 |
| 452.94 | 4.10 | 4.10 |
| 403.49 | 4.42 | 4.42 |
| 369.37 | 3.59 | 3.59 |
| 417.51 | 3.42 | 3.42 |
| 432.52 | 4.10 | 4.10 |
| 439.46 | 4.15 | 4.15 |
| 404.47 | 4.39 | 4.39 |
| 468.50 | 3.98 | 3.98 |
| 446.55 | 4.01 | 4.01 |
| 468.50 | 4.19 | 4.19 |
| 455.47 | 3.12 | 3.12 |
| 454.48 | 3.73 | 3.73 |
| 440.45 | 3.34 | 3.34 |
| 413.38 | 3.29 | 3.29 |
| 402.50 | 3.96 | 3.96 |
| 432.52 | 3.62 | 3.62 |
| 452.46 | 3.48 | 3.48 |
| 455.46 | 4.15 | 4.15 |
| 418.50 | 3.45 | 3.45 |
| 470.48 | 3.43 | 3.43 |
| 432.52 | 3.76 | 3.76 |
| 426.42 | 2.95 | 2.95 |
| 440.45 | 3.29 | 3.29 |
| 468.50 | 4.12 | 4.12 |
| 455.47 | 3.12 | 3.12 |