Basic Information
ID: ALA4822790
Type: Binding
Description: Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for 3 mins followed by substrate addition and measured after 20 mins by fluorescence analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4822790
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.53 | 5.04 | 5.04 |
| 340.18 | 3.06 | 3.06 |
| 358.42 | 4.63 | 4.63 |
| 340.43 | 4.60 | 4.60 |
| 278.36 | 3.66 | 3.66 |
| 356.43 | 4.31 | 4.31 |
| 326.40 | 4.30 | 4.30 |
| 344.39 | 4.44 | 4.44 |
| 332.45 | 4.42 | 4.42 |
| 376.46 | 5.45 | 5.45 |
| 360.50 | 5.04 | 5.04 |
| 405.30 | 5.06 | 5.06 |
| 356.43 | 4.31 | 4.31 |
| 332.43 | 4.36 | 4.36 |
| 360.84 | 4.95 | 4.95 |
| 394.40 | 5.32 | 5.32 |
| 462.39 | 6.33 | 6.33 |
| 278.36 | 3.58 | 3.58 |
| 298.77 | 3.92 | 3.92 |
| 264.33 | 3.27 | 3.27 |
| 405.30 | 5.06 | 5.06 |
| 371.40 | 4.20 | 4.20 |
| 340.43 | 4.60 | 4.60 |
| 276.34 | 3.63 | 3.63 |
| 264.33 | 3.46 | 3.46 |
| 340.43 | 4.60 | 4.60 |
| 340.43 | 4.60 | 4.60 |
| 340.43 | 4.60 | 4.60 |
| 264.33 | 2.72 | 2.72 |