Assay Report Card

Basic Information

ID: ALA4822797

Type: Binding

Description: Potency index, ratio of BNPP IC50 to test compound IC50 for Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for 3 mins followed by substrate addition and measured after 20 mins by fluorescence analysis

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
360.505.045.04