Basic Information
ID: ALA4822812
Type: Binding
Description: Antagonist activity at human ERbeta expressed in human HEK293T cells assessed as inhibition of 17beta-estradiol-induced transcriptional activities by measuring ERE driven reporter gene expression measured after 24 hrs by dual luciferase reporter gene assay relative to 17beta-estradiol
Organism: Homo sapiens
Cell type: HEK293T
Activity Charts
Bioactivity
Activity Types for Assay ALA4822812
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.49 | 3.96 | 3.96 |
| 517.53 | 4.95 | 4.95 |
| 618.75 | 6.06 | 6.06 |
| 620.72 | 5.38 | 5.38 |
| 634.75 | 5.68 | 5.68 |
| 634.75 | 5.68 | 5.68 |
| 639.17 | 6.33 | 6.33 |
| 702.75 | 6.61 | 6.61 |
| 648.78 | 6.07 | 6.07 |
| 634.75 | 5.77 | 5.77 |
| 639.17 | 6.33 | 6.33 |
| 702.75 | 6.61 | 6.61 |
| 697.65 | 6.83 | 6.83 |
| 653.20 | 6.72 | 6.72 |
| 618.75 | 5.98 | 5.98 |
| 632.78 | 6.37 | 6.37 |
| 632.78 | 6.37 | 6.37 |
| 672.72 | 6.61 | 6.61 |
| 686.75 | 6.91 | 6.91 |
| 653.20 | 6.72 | 6.72 |