Basic Information
ID: ALA4822878
Type: Binding
Description: Inhibition of N-terminal GST-fused human full length recombinant MNK1 (1 to 424 residues) expressed in baculovirus-infected Sf21 cells using TATKSGSTTKNR as substrate preincubated with enzyme and substrate for 10 mins followed by ATP addition and measured after 40 mins by ADP-glo luminescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf21
Target: MAP kinase-interacting serine/threonine-protein kinase MNK1(ALA4718)
Document: ALA4819134
Inhibition of N-terminal GST-fused human full length recombinant MNK1 (1 to 424 residues) expressed in baculovirus-infected Sf21 cells using TATKSGSTTKNR as substrate preincubated with enzyme and substrate for 10 mins followed by ATP addition and measured after 40 mins by ADP-glo luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4822878
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.46 | 4.01 | 4.01 |
| 434.50 | 4.69 | 4.69 |
| 447.54 | 4.78 | 4.78 |
| 448.53 | 4.17 | 4.17 |
| 447.54 | 4.78 | 4.78 |
| 515.66 | 6.31 | 6.31 |
| 448.53 | 4.17 | 4.17 |
| 434.50 | 4.69 | 4.69 |
| 448.53 | 4.17 | 4.17 |
| 517.63 | 5.15 | 5.15 |
| 433.52 | 4.26 | 4.26 |
| 448.53 | 4.17 | 4.17 |
| 433.52 | 4.26 | 4.26 |
| 434.50 | 4.69 | 4.69 |
| 447.54 | 4.78 | 4.78 |
| 448.53 | 4.17 | 4.17 |
| 448.53 | 4.17 | 4.17 |