Basic Information
ID: ALA4822986
Type: Functional
Description: Potency index, ratio of benznidazole IC50 to test compound IC50 for trypanocidal activity against Trypanosoma cruzi Y strain bloodstream trypomastigotes isolated from infected in Albino Swiss mouse assessed as lysis of parasite in presence of 5 % mouse blood incubated for 24 hrs by Neubauer chamber method
Format: BAO_0000218
Organism: Trypanosoma cruzi
Strain: Y
Target: Trypanosoma cruzi(ALA368)
Document: ALA4819141
Potency index, ratio of benznidazole IC50 to test compound IC50 for trypanocidal activity against Trypanosoma cruzi Y strain bloodstream trypomastigotes isolated from infected in Albino Swiss mouse assessed as lysis of parasite in presence of 5 % mouse blood incubated for 24 hrs by Neubauer chamber method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4822986
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.28 | 3.16 | 3.16 |
| 318.25 | 3.87 | 3.87 |
| 262.31 | 3.77 | 3.77 |
| 290.36 | 4.45 | 4.45 |