Basic Information
ID: ALA4823343
Type: Binding
Description: Inhibition of recombinant human C-terminal His-fusion tagged/N-terminal Strep2 tagged HDAC8 (1 to 377 residues) expressed in insect cells using Boc-Lys(TFA)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 90 mins by fluorimetry
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4823343
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 305.33 | 1.90 | 1.90 |
| 317.35 | 1.96 | 1.96 |
| 317.35 | 1.96 | 1.96 |
| 318.33 | 1.36 | 1.36 |
| 316.36 | 2.57 | 2.57 |