Basic Information
ID: ALA4823673
Type: Binding
Description: Protac activity at SHP2/CRBN in human MV4-11 cells assessed as SHP2 degradation at 8 nM measured after 12 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: MV4-11
Activity Charts
Bioactivity
Activity Types for Assay ALA4823673
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 945.59 | 6.06 | 6.06 |
| 917.53 | 5.27 | 5.27 |
| 931.56 | 5.67 | 5.67 |
| 903.51 | 4.88 | 4.88 |
| 951.50 | 2.59 | 2.59 |
| 973.64 | 6.84 | 6.84 |
| 951.50 | 2.59 | 2.59 |
| 907.45 | 2.58 | 2.58 |
| 959.61 | 6.45 | 6.45 |
| 979.56 | 3.37 | 3.37 |
| 863.40 | 2.56 | 2.56 |
| 979.56 | 3.37 | 3.37 |
| 907.45 | 2.58 | 2.58 |
| 863.40 | 2.56 | 2.56 |