Basic Information
ID: ALA4823699
Type: Binding
Description: Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as substrate incubated for 30 mins in presence of ATP by ELISA
Format: BAO_0000357
Organism: Homo sapiens
Target: Serine-protein kinase ATM(ALA3797)
Document: ALA4823251
Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as substrate incubated for 30 mins in presence of ATP by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4823699
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.49 | 4.21 | 4.21 |
| 381.52 | 3.59 | 3.59 |
| 353.47 | 2.81 | 2.81 |
| 369.47 | 2.05 | 2.05 |
| 420.53 | 4.66 | 4.66 |
| 368.48 | 2.60 | 2.60 |
| 407.50 | 3.75 | 3.75 |
| 339.44 | 2.42 | 2.42 |
| 340.43 | 2.23 | 2.23 |
| 354.45 | 2.06 | 2.06 |
| 382.51 | 2.99 | 2.99 |
| 406.51 | 3.94 | 3.94 |
| 366.46 | 2.06 | 2.06 |
| 339.44 | 2.28 | 2.28 |
| 365.48 | 2.67 | 2.67 |
| 352.44 | 1.67 | 1.67 |
| 352.44 | 1.67 | 1.67 |
| 375.42 | 2.67 | 2.67 |
| 351.45 | 2.28 | 2.28 |
| 357.43 | 2.37 | 2.37 |
| 366.46 | 2.06 | 2.06 |
| 407.50 | 3.75 | 3.75 |
| 365.48 | 2.67 | 2.67 |
| 420.53 | 3.95 | 3.95 |
| 406.51 | 3.94 | 3.94 |
| 367.49 | 3.20 | 3.20 |
| 339.44 | 2.42 | 2.42 |
| 339.44 | 2.42 | 2.42 |
| 351.45 | 2.28 | 2.28 |
| 407.50 | 3.75 | 3.75 |
| 340.43 | 2.23 | 2.23 |
| 406.51 | 3.94 | 3.94 |