Basic Information
ID: ALA4823710
Type: Binding
Description: Selectivity ratio of Ki for DNA-PK isolated from human HeLa nuclear extract using full length His-tagged p53 as substrate measured after 75 mins in presence of ATP by HTRF assay to Ki for full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as substrate incubated for 30 mins in presence of ATP by ELISA
Format: BAO_0000019
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4823251
Selectivity ratio of Ki for DNA-PK isolated from human HeLa nuclear extract using full length His-tagged p53 as substrate measured after 75 mins in presence of ATP by HTRF assay to Ki for full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as substrate incubated for 30 mins in presence of ATP by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4823710
Ratio Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 354.45 | 2.06 | 2.06 |
| 365.48 | 2.67 | 2.67 |
| 367.49 | 3.20 | 3.20 |
| 351.45 | 2.28 | 2.28 |