Basic Information
ID: ALA4824073
Type: Binding
Description: Selectivity ratio of IC50 for His-tagged BRD4 BD1 (unknown origin) using biotinylated-JQ1 peptide as substrate to IC50 for His-tagged CBP (unknown origin) using biotinylated-H3K56ac peptide as substrate incubated for 1 hr by AlphaScreen assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4823258
Selectivity ratio of IC50 for His-tagged BRD4 BD1 (unknown origin) using biotinylated-JQ1 peptide as substrate to IC50 for His-tagged CBP (unknown origin) using biotinylated-H3K56ac peptide as substrate incubated for 1 hr by AlphaScreen assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4824073
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 509.05 | 5.48 | 5.48 |
| 468.60 | 6.66 | 6.66 |
| 434.54 | 5.23 | 5.23 |
| 388.52 | 5.60 | 5.60 |
| 414.55 | 6.14 | 6.14 |
| 488.68 | 7.42 | 7.42 |
| 523.12 | 8.07 | 8.07 |
| 401.55 | 6.01 | 6.01 |
| 479.02 | 6.80 | 6.80 |
| 379.55 | 6.25 | 6.25 |
| 446.55 | 5.14 | 5.14 |
| 479.63 | 6.51 | 6.51 |
| 458.61 | 6.53 | 6.53 |
| 450.59 | 6.98 | 6.98 |
| 452.56 | 6.01 | 6.01 |
| 488.68 | 7.42 | 7.42 |
| 487.00 | 6.67 | 6.67 |
| 444.62 | 7.02 | 7.02 |
| 496.66 | 6.78 | 6.78 |
| 430.55 | 5.95 | 5.95 |
| 418.54 | 5.61 | 5.61 |
| 493.05 | 7.19 | 7.19 |
| 444.58 | 6.14 | 6.14 |
| 474.65 | 7.03 | 7.03 |
| 502.70 | 7.81 | 7.81 |
| 458.61 | 6.53 | 6.53 |
| 448.52 | 5.04 | 5.04 |
| 493.05 | 7.19 | 7.19 |
| 404.51 | 5.22 | 5.22 |
| 472.63 | 6.92 | 6.92 |
| 474.61 | 6.15 | 6.15 |
| 416.53 | 6.03 | 6.03 |
| 449.60 | 6.72 | 6.72 |
| 475.59 | 4.14 | 4.14 |
| 466.63 | 6.77 | 6.77 |