Basic Information
ID: ALA4824266
Type: Functional
Description: Leishmanicidal activity against axenic amastigote stage of Leishmania infantum MCAN/ES/89/IPZ229/1/89 infected in human THP-1 macrophage cells assessed as reduction in intracellular amastigotes incubated for 24 hrs by propidium iodide staining based flow cytometry
Organism: Leishmania infantum
Strain: MCAN/ES/89/IPZ229/1/89
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA4824266
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 924.09 | 0.71 | 0.71 |
| 407.58 | 5.68 | 5.68 |
| 721.81 | 5.53 | 5.53 |
| 581.75 | 4.39 | 4.39 |
| 695.77 | 5.01 | 5.01 |
| 607.78 | 4.90 | 4.90 |
| 1157.19 | 5.80 | 5.80 |
| 707.78 | 5.14 | 5.14 |
| 672.73 | 4.10 | 4.10 |
| 537.76 | 6.88 | 6.88 |
| 785.85 | 7.20 | 7.20 |
| 1394.77 | ||
| 645.71 | 3.86 | 3.86 |