Basic Information
ID: ALA4824533
Type: Binding
Description: Inhibition of Keap1-Nrf2 interaction in mouse peritoneal macrophages assessed as increase in nuclear translocation of Nrf2 by measuring decrease in cytosolic Nrf2 level at 10 uM measured after 3 to 6 hrs by Western blot analysis
Format: BAO_0000220
Organism: Mus musculus
Cell type: Peritoneal macrophage
Subcellular Fraction: Cytosol
Target: KEAP1/NRF2(ALA4296107)
Document: ALA4823275
Inhibition of Keap1-Nrf2 interaction in mouse peritoneal macrophages assessed as increase in nuclear translocation of Nrf2 by measuring decrease in cytosolic Nrf2 level at 10 uM measured after 3 to 6 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4824533
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 177.29 | 1.25 | 1.25 |
| 729.88 | 2.81 | 2.81 |
| 597.68 | 1.79 | 1.79 |