Basic Information
ID: ALA4824985
Type: Binding
Description: Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45 mins followed by ATP addition and then later incubated with substrate for 90 mins by absorption spectrophotometric assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Pyruvate dehydrogenase kinase isoform 2(ALA3861)
Document: ALA4823293
Inhibition of human PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45 mins followed by ATP addition and then later incubated with substrate for 90 mins by absorption spectrophotometric assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4824985
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 161.20 | 1.92 | 1.92 |
| 176.22 | 1.50 | 1.50 |
| 200.24 | 2.09 | 2.09 |
| 189.26 | 2.53 | 2.53 |
| 190.25 | 1.96 | 1.96 |
| 201.27 | 2.79 | 2.79 |
| 223.28 | 3.30 | 3.30 |
| 189.26 | 2.48 | 2.48 |
| 303.55 | 2.04 | 2.04 |
| 222.29 | 3.90 | 3.90 |
| 209.68 | 2.87 | 2.87 |
| 254.13 | 2.98 | 2.98 |
| 223.71 | 3.18 | 3.18 |
| 242.11 | 3.61 | 3.61 |
| 238.68 | 1.59 | 1.59 |
| 208.26 | 3.59 | 3.59 |