Basic Information
ID: ALA4824986
Type: Binding
Description: Inhibition of human PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrate preincubated with enzyme complex for 45 mins followed by ATP addition and then later incubated with substrate for 90 mins by absorption spectrophotometric assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4824986
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 161.20 | 1.92 | 1.92 |
| 176.22 | 1.50 | 1.50 |
| 200.24 | 2.09 | 2.09 |
| 189.26 | 2.53 | 2.53 |
| 190.25 | 1.96 | 1.96 |
| 201.27 | 2.79 | 2.79 |
| 223.28 | 3.30 | 3.30 |
| 189.26 | 2.48 | 2.48 |
| 303.55 | 2.04 | 2.04 |
| 222.29 | 3.90 | 3.90 |
| 209.68 | 2.87 | 2.87 |
| 254.13 | 2.98 | 2.98 |
| 223.71 | 3.18 | 3.18 |
| 242.11 | 3.61 | 3.61 |
| 238.68 | 1.59 | 1.59 |
| 208.26 | 3.59 | 3.59 |