Basic Information
ID: ALA4825138
Type: Binding
Description: Inhibition of human GluN1-1a/NR2A receptor expressed in transgenic mouse fibroblast cells assessed as inhibition of L-glutamate-induced excitotoxicity by measuring LDH activity by cell based assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Fibroblast
Target: Glutamate NMDA receptor; GRIN1/GRIN2A(ALA1907604)
Document: ALA4823302
Inhibition of human GluN1-1a/NR2A receptor expressed in transgenic mouse fibroblast cells assessed as inhibition of L-glutamate-induced excitotoxicity by measuring LDH activity by cell based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4825138
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 179.31 | 2.69 | 2.69 |
| 421.53 | 6.41 | 6.41 |
| 451.55 | 6.42 | 6.42 |
| 592.56 | 7.35 | 7.35 |
| 435.55 | 6.72 | 6.72 |
| 439.52 | 6.55 | 6.55 |
| 563.46 | 5.84 | 5.84 |
| 577.49 | 6.15 | 6.15 |
| 581.45 | 5.98 | 5.98 |
| 593.49 | 5.85 | 5.85 |