Basic Information
ID: ALA4825141
Type: Binding
Description: Inhibition of human GluN1-1a/NR2B receptor expressed in transgenic mouse fibroblast cells assessed as inhibition of L-glutamate-induced excitotoxicity at 20 uM by measuring LDH activity by cell based assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Fibroblast
Target: Nicotinic acetylcholine receptor alpha6/alpha3/beta4(ALA3137276)
Document: ALA4823302
Inhibition of human GluN1-1a/NR2B receptor expressed in transgenic mouse fibroblast cells assessed as inhibition of L-glutamate-induced excitotoxicity at 20 uM by measuring LDH activity by cell based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4825141
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.50 | 4.36 | 4.36 |
| 168.20 | 2.72 | 2.72 |
| 199.28 | 3.89 | 3.89 |
| 182.23 | 3.02 | 3.02 |
| 310.14 | 2.68 | 2.68 |
| 262.36 | 3.73 | 3.73 |
| 186.26 | 2.16 | 2.16 |
| 460.63 | 8.12 | 8.12 |
| 496.74 | 7.00 | 7.00 |
| 198.22 | 2.72 | 2.72 |
| 328.13 | 2.28 | 2.28 |
| 292.38 | 3.73 | 3.73 |
| 339.24 | 3.66 | 3.66 |
| 276.38 | 4.03 | 4.03 |
| 340.16 | 2.15 | 2.15 |
| 280.35 | 3.87 | 3.87 |
| 439.58 | 5.85 | 5.85 |
| 186.19 | 2.86 | 2.86 |
| 324.17 | 2.45 | 2.45 |