Basic Information
ID: ALA4825255
Type: Functional
Description: Antiviral activity against SARS-CoV-2 nCoV-2019BetaCoV/Wuhan/WIV04/ infected in African green monkey Vero E6 cells assessed as inhibition of viral replication at 5 uM when host cells were pretreated for 1 hr followed by viral infection then followed by removal of infected supernatant and subsequent culture addition with fresh compounds and measured after 24 hrs by qRT-PCR method relative to control
Organism: Severe acute respiratory syndrome coronavirus 2
Strain: nCoV-2019BetaCoV/Wuhan/WIV04/
Cell type: Vero E6
Activity Charts
Bioactivity
Activity Types for Assay ALA4825255
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 291.27 | -1.86 | -1.86 |
| 268.25 | -0.56 | -0.56 |
| 602.59 | 2.31 | 2.31 |
| 309.26 | -1.72 | -1.72 |
| 308.29 | -1.79 | -1.79 |
| 431.45 | 0.56 | 0.56 |
| 296.28 | -2.39 | -2.39 |
| 417.16 | -1.25 | -1.25 |
| 282.26 | -1.32 | -1.32 |
| 431.45 | 0.56 | 0.56 |
| 316.28 | -1.99 | -1.99 |
| 305.29 | -1.20 | -1.20 |
| 306.32 | -0.80 | -0.80 |
| 309.28 | -2.89 | -2.89 |
| 361.36 | -0.65 | -0.65 |
| 307.31 | -0.85 | -0.85 |
| 463.32 | -1.32 | -1.32 |
| 361.36 | -0.65 | -0.65 |
| 292.25 | -1.73 | -1.73 |
| 286.24 | -0.26 | -0.26 |
| 325.71 | -1.20 | -1.20 |
| 317.31 | -1.30 | -1.30 |