Antiviral activity against SARS-CoV-2 nCoV-2019BetaCoV/Wuhan/WIV04/ infected in African green monkey Vero E6 cells assessed as inhibition of viral rep...

Basic Information

ID: ALA4825256

Type: Functional

Description: Antiviral activity against SARS-CoV-2 nCoV-2019BetaCoV/Wuhan/WIV04/ infected in African green monkey Vero E6 cells assessed as inhibition of viral replication at 10 uM when host cells were pretreated for 1 hr followed by viral infection then followed by removal of infected supernatant and subsequent culture addition with fresh compounds and measured after 24 hrs by qRT-PCR method relative to control

Format: BAO_0000218

Organism: Severe acute respiratory syndrome coronavirus 2

Strain: nCoV-2019BetaCoV/Wuhan/WIV04/

Cell type: Vero E6

Target:  SARS-CoV-2(ALA4303835)

Document:  ALA4823313

Antiviral activity against SARS-CoV-2 nCoV-2019BetaCoV/Wuhan/WIV04/ infected in African green monkey Vero E6 cells assessed as inhibition of viral replication at 10 uM when host cells were pretreated for 1 hr followed by viral infection then followed by removal of infected supernatant and subsequent culture addition with fresh compounds and measured after 24 hrs by qRT-PCR method relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
309.26-1.72-1.72
405.410.300.30
620.572.452.45