Basic Information
ID: ALA4825419
Type: Binding
Description: Inhibition of ZIKV NS2B-NS3 protease expressed in Escherichia coli BL21(DE3) using Boc-Gly-Arg-Arg-AMC as substrate by FRET assay
Format: BAO_0000019
Organism: Zika virus
Target: Genome polyprotein(ALA4523954)
Document: ALA4823320
Inhibition of ZIKV NS2B-NS3 protease expressed in Escherichia coli BL21(DE3) using Boc-Gly-Arg-Arg-AMC as substrate by FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4825419
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 320.76 | 3.61 | 3.61 |
| 382.44 | 3.56 | 3.56 |
| 286.31 | 2.96 | 2.96 |
| 380.40 | 3.48 | 3.48 |
| 300.34 | 3.27 | 3.27 |
| 268.27 | 2.83 | 2.83 |
| 286.31 | 2.96 | 2.96 |
| 362.41 | 4.63 | 4.63 |
| 412.21 | 3.56 | 3.56 |
| 449.55 | 3.35 | 3.35 |
| 419.46 | 3.99 | 3.99 |
| 483.57 | 3.54 | 3.54 |
| 269.26 | 3.10 | 3.10 |
| 449.55 | 3.35 | 3.35 |
| 280.28 | 2.90 | 2.90 |
| 383.43 | 2.95 | 2.95 |
| 456.29 | 4.62 | 4.62 |
| 476.51 | 3.47 | 3.47 |
| 407.47 | 2.32 | 2.32 |
| 285.32 | 3.56 | 3.56 |
| 366.37 | 3.09 | 3.09 |
| 366.37 | 3.09 | 3.09 |
| 376.44 | 4.48 | 4.48 |
| 529.67 | 4.23 | 4.23 |
| 449.49 | 3.39 | 3.39 |
| 445.33 | 5.78 | 5.78 |
| 412.21 | 3.56 | 3.56 |