Basic Information
ID: ALA4825467
Type: Binding
Description: Inhibition of Escherichia coli topoisomerase 4 assessed as reduction in decatenation using supercoiled pNO1 plasmid DNA as substrate incubated for 30 mins by fluorimetric assay
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA4825467
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 448.53 | 1.09 | 1.09 |
| 411.94 | 3.48 | 3.48 |
| 455.40 | 4.20 | 4.20 |
| 410.95 | 4.09 | 4.09 |
| 428.94 | 4.23 | 4.23 |
| 491.38 | 4.48 | 4.48 |
| 538.38 | 4.32 | 4.32 |
| 491.38 | 4.48 | 4.48 |
| 473.39 | 4.34 | 4.34 |
| 502.40 | 4.04 | 4.04 |
| 491.38 | 4.48 | 4.48 |
| 411.94 | 3.48 | 3.48 |
| 446.93 | 4.37 | 4.37 |
| 520.39 | 4.18 | 4.18 |