Basic Information
ID: ALA4825491
Type: Functional
Description: Selectivity index, ratio of IC50 for antileishmanial activity against wild type Leishmania donovani promastigotes to IC50 for antileishmanial activity against Leishmania donovani LdBOB derived from MHOM/SD/62/1 S-CL2D promastigotes overexpressing NTR1
Format: BAO_0000019
Organism: Leishmania donovani
Target: Unchecked(ALA612545)
Document: ALA4823323
Selectivity index, ratio of IC50 for antileishmanial activity against wild type Leishmania donovani promastigotes to IC50 for antileishmanial activity against Leishmania donovani LdBOB derived from MHOM/SD/62/1 S-CL2D promastigotes overexpressing NTR1: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4825491
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 287.30 | 0.64 | 0.64 |
| 262.29 | 2.79 | 2.79 |
| 212.21 | 1.92 | 1.92 |
| 170.12 | 0.75 | 0.75 |
| 186.19 | 1.22 | 1.22 |
| 246.22 | 2.32 | 2.32 |
| 228.27 | 2.38 | 2.38 |