Basic Information
ID: ALA4825505
Type: Toxicity
Description: Selectivity index, ratio of CC50 for cytotoxicity against BALB/c mouse peritoneal macrophages assessed as reduction in cell viability incubated for 72 hrs by resazurin dye based fluorescence assay to IC50 for antileishmanial activity against intracellular Leishmania amazonensis MHOM/BR/77/LTB 0016 amastigotes infected in BALB/c mouse peritoneal macrophage
Format: BAO_0000219
Target: ADMET(ALA612558)
Document: ALA4823323
Selectivity index, ratio of CC50 for cytotoxicity against BALB/c mouse peritoneal macrophages assessed as reduction in cell viability incubated for 72 hrs by resazurin dye based fluorescence assay to IC50 for antileishmanial activity against intracellular Leishmania amazonensis MHOM/BR/77/LTB 0016 amastigotes infected in BALB/c mouse peritoneal macrophage: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4825505
Selectivity Index
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.58 | 5.68 | 5.68 |
| 141.08 | 1.00 | 1.00 |
| 125.13 | 0.84 | 0.84 |
| 262.29 | 2.79 | 2.79 |
| 212.21 | 1.92 | 1.92 |
| 170.12 | 0.75 | 0.75 |
| 141.19 | 1.31 | 1.31 |
| 157.15 | 1.47 | 1.47 |
| 186.19 | 1.22 | 1.22 |
| 180.16 | 1.15 | 1.15 |
| 246.22 | 2.32 | 2.32 |