Basic Information
ID: ALA4825607
Type: ADME
Description: Inhibition of recombinant CYP3A4 (unknown origin) using BFC as substrate at 1 uM measured after 30 mins in presence of NADPH generating system by fluorescence assay relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: Cytochrome P450 3A4(ALA340)
Document: ALA4823330
Inhibition of recombinant CYP3A4 (unknown origin) using BFC as substrate at 1 uM measured after 30 mins in presence of NADPH generating system by fluorescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4825607
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 159.23 | 1.08 | 1.08 |
| 330.43 | 1.40 | 1.40 |
| 329.45 | 1.95 | 1.95 |
| 407.36 | 3.31 | 3.31 |
| 329.45 | 1.95 | 1.95 |
| 421.38 | 3.70 | 3.70 |
| 421.38 | 3.70 | 3.70 |
| 421.38 | 3.70 | 3.70 |
| 316.41 | 1.01 | 1.01 |
| 421.38 | 3.70 | 3.70 |
| 384.52 | 2.57 | 2.57 |
| 421.38 | 3.70 | 3.70 |
| 358.49 | 2.18 | 2.18 |
| 328.46 | 2.46 | 2.46 |
| 393.33 | 2.93 | 2.93 |
| 342.49 | 2.94 | 2.94 |
| 419.57 | 4.00 | 4.00 |
| 421.38 | 3.70 | 3.70 |
| 386.54 | 2.96 | 2.96 |
| 329.45 | 1.95 | 1.95 |
| 421.38 | 3.70 | 3.70 |
| 419.37 | 3.46 | 3.46 |
| 372.51 | 2.57 | 2.57 |
| 407.36 | 3.31 | 3.31 |
| 385.56 | 3.37 | 3.37 |
| 394.52 | 3.56 | 3.56 |
| 404.56 | 3.97 | 3.97 |
| 302.38 | 0.45 | 0.45 |
| 407.36 | 3.31 | 3.31 |
| 421.38 | 3.70 | 3.70 |
| 419.57 | 4.00 | 4.00 |
| 367.50 | 2.81 | 2.81 |
| 372.51 | 2.57 | 2.57 |
| 407.36 | 3.31 | 3.31 |
| 329.45 | 1.95 | 1.95 |
| 344.46 | 1.79 | 1.79 |
| 421.38 | 3.70 | 3.70 |