Basic Information
ID: ALA4825637
Type: Binding
Description: Inhibition of gp120 (Gln 105 residue) in HIV-1 JR-FL infected in dog Cf2Th-CD4/CCR5 cells assessed as inhibition of viral entry incubated for 30 mins prior to infection and and further incubated for 48 to 72 hrs in presence of firefly D-luciferin free acid and ATP by single-round infection luciferase assay
Organism: Human immunodeficiency virus 1
Strain: JR-FL
Cell type: Cf2Th-CD4/CCR5
Activity Charts
Bioactivity
Activity Types for Assay ALA4825637
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 674.96 | 1.65 | 1.65 |
| 733.04 | 1.96 | 1.96 |
| 763.06 | 1.32 | 1.32 |
| 761.05 | 1.53 | 1.53 |
| 763.06 | 1.32 | 1.32 |
| 763.06 | 1.32 | 1.32 |
| 763.06 | 1.32 | 1.32 |
| 731.07 | 3.38 | 3.38 |
| 733.04 | 1.96 | 1.96 |
| 729.05 | 3.16 | 3.16 |
| 763.06 | 1.32 | 1.32 |
| 729.05 | 3.16 | 3.16 |