ID: ALA4825799
Type: Binding
Description: Inhibition of JAK2/TYK2 signaling pathway in human whole blood assessed as reduction in IL-23 induced STAT3 phosphorylation by measuring free plasma concentration incubated for 60 mins followed by IL-23 addition and measured after 20 mins by fluorescence assay
Organism: Homo sapiens
Tissue: Blood
Bioactivity
Activity Types for Assay ALA4825799
fIC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
479.42 | 3.79 | 3.79 |