Protac activity at CRBN/EGFR exon 19 deletion mutant in human PC-9 cells assessed as induction of EGFR degradation at >10 nM measured after 48 hrs by ...

Basic Information

ID: ALA4826142

Type: Binding

Description: Protac activity at CRBN/EGFR exon 19 deletion mutant in human PC-9 cells assessed as induction of EGFR degradation at >10 nM measured after 48 hrs by Western blot assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: PC-9

Target: Protein cereblon/Epidermal growth factor receptor(ALA4523680)

Document: ALA4825665

Protac activity at CRBN/EGFR exon 19 deletion mutant in human PC-9 cells assessed as induction of EGFR degradation at >10 nM measured after 48 hrs by Western blot assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4826142

Activity

Total(2)

Parent Molecular Weight	ALogP	Polar Surface Area
868.37	5.67	5.67
854.34	5.28	5.28

Parent Molecular Weight

ALogP

Polar Surface Area

868.37

5.67

854.34

5.28

Protac activity at CRBN/EGFR exon 19 deletion mutant in human PC-9 cells assessed as induction of EGFR degradation at >10 nM measured after 48 hrs by ...

Basic Information

Activity Charts

Compound Summary