Basic Information
ID: ALA4826146
Type: Binding
Description: Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as induction of EGFR degradation at 300 nM measured after 8 to 72 hrs by Western blot assay relative to control
Organism: Homo sapiens
Cell type: NCI-H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA4826146
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 868.37 | 5.67 | 5.67 |
| 854.34 | 5.28 | 5.28 |