Basic Information
ID: ALA4826147
Type: Binding
Description: Protac activity at CRBN/EGFR exon19 deletion/T790M mutant in human PC-9 cells transfected with BRCA1 assessed as induction of EGFR degradation at 1 to 1000 nM measured after 16 hrs by Western blot assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: PC-9
Target: Protein cereblon/Epidermal growth factor receptor(ALA4523680)
Document: ALA4825665
Protac activity at CRBN/EGFR exon19 deletion/T790M mutant in human PC-9 cells transfected with BRCA1 assessed as induction of EGFR degradation at 1 to 1000 nM measured after 16 hrs by Western blot assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4826147
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 868.37 | 5.67 | 5.67 |
| 854.34 | 5.28 | 5.28 |