Basic Information
ID: ALA4826152
Type: Binding
Description: Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as induction of EGFR degradation at 300 nM pretreated for 24 hrs followed by compound washout and subsequent addition of fresh medium by Western blot assay relative to control
Organism: Homo sapiens
Cell type: NCI-H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA4826152
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 868.37 | 5.67 | 5.67 |
| 854.34 | 5.28 | 5.28 |