Basic Information
ID: ALA4826153
Type: Binding
Description: Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as induction of EGFR degradation at 300 nM incubated for 24 hrs followed by compound washout and measured 72 hrs after drug removal by Western blot assay
Organism: Homo sapiens
Cell type: NCI-H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA4826153
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 868.37 | 5.67 | 5.67 |
| 854.34 | 5.28 | 5.28 |