Basic Information
ID: ALA4826154
Type: Binding
Description: Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as decrease in cell doubling time at 100 to 300 nM measured after 24 hrs by CSFE staining based fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: NCI-H1975
Target: Protein cereblon/Epidermal growth factor receptor(ALA4523680)
Document: ALA4825665
Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as decrease in cell doubling time at 100 to 300 nM measured after 24 hrs by CSFE staining based fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4826154
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 868.37 | 5.67 | 5.67 |
| 854.34 | 5.28 | 5.28 |