Assay Report Card

Basic Information

ID: ALA4826154

Type: Binding

Description: Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as decrease in cell doubling time at 100 to 300 nM measured after 24 hrs by CSFE staining based fluorescence assay

Organism: Homo sapiens

Cell type: NCI-H1975

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
868.375.675.67
854.345.285.28