Basic Information
ID: ALA4826155
Type: Functional
Description: Cell cycle arrest in human NCI-H1975 cells expressing EGFR L858R/T790M mutant assessed as increase of cell population in G0/G1 phase at 0.03 to 0.5 nM measured after 48 hrs by RNaseA/propidium iodide staining based flow cytometry
Format: BAO_0000219
Organism: Homo sapiens
Cell type: NCI-H1975
Target: NCI-H1975(ALA614348)
Document: ALA4825665
Cell cycle arrest in human NCI-H1975 cells expressing EGFR L858R/T790M mutant assessed as increase of cell population in G0/G1 phase at 0.03 to 0.5 nM measured after 48 hrs by RNaseA/propidium iodide staining based flow cytometry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4826155
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 868.37 | 5.67 | 5.67 |
| 854.34 | 5.28 | 5.28 |