Assay Report Card

Basic Information

ID: ALA4826155

Type: Functional

Description: Cell cycle arrest in human NCI-H1975 cells expressing EGFR L858R/T790M mutant assessed as increase of cell population in G0/G1 phase at 0.03 to 0.5 nM measured after 48 hrs by RNaseA/propidium iodide staining based flow cytometry

Organism: Homo sapiens

Cell type: NCI-H1975

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
868.375.675.67
854.345.285.28