Cell cycle arrest in human NCI-H1975 cells expressing EGFR L858R/T790M mutant assessed as decrease of cell population in S phase at 0.03 to 0.5 nM mea...

Basic Information

ID: ALA4826156

Type: Functional

Description: Cell cycle arrest in human NCI-H1975 cells expressing EGFR L858R/T790M mutant assessed as decrease of cell population in S phase at 0.03 to 0.5 nM measured after 48 hrs by RNaseA/propidium iodide staining based flow cytometry

Format: BAO_0000219

Organism: Homo sapiens

Cell type: NCI-H1975

Target: NCI-H1975(ALA614348)

Document: ALA4825665

Cell cycle arrest in human NCI-H1975 cells expressing EGFR L858R/T790M mutant assessed as decrease of cell population in S phase at 0.03 to 0.5 nM measured after 48 hrs by RNaseA/propidium iodide staining based flow cytometry: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4826156

Activity

Total(2)

Parent Molecular Weight	ALogP	Polar Surface Area
868.37	5.67	5.67
854.34	5.28	5.28

Parent Molecular Weight

ALogP

Polar Surface Area

868.37

5.67

854.34

5.28

Cell cycle arrest in human NCI-H1975 cells expressing EGFR L858R/T790M mutant assessed as decrease of cell population in S phase at 0.03 to 0.5 nM mea...

Basic Information

Activity Charts

Compound Summary