Basic Information
ID: ALA4826164
Type: Binding
Description: Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as induction of EGFR degradation at 0.3 uM pre-incubated for 2 hrs in the presence of Bafilomycin A1 and measured after 16 hrs by Western blot assay
Organism: Homo sapiens
Cell type: NCI-H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA4826164
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 868.37 | 5.67 | 5.67 |
| 854.34 | 5.28 | 5.28 |