Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as increase in ratio of LC3B2 to LC3B1 at 30 to 300 nM measured afte...

Basic Information

ID: ALA4826165

Type: Binding

Description: Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as increase in ratio of LC3B2 to LC3B1 at 30 to 300 nM measured after 16 hrs by Western blot assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: NCI-H1975

Target: Protein cereblon/Epidermal growth factor receptor(ALA4523680)

Document: ALA4825665

Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as increase in ratio of LC3B2 to LC3B1 at 30 to 300 nM measured after 16 hrs by Western blot assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4826165

Activity

Total(2)

Parent Molecular Weight	ALogP	Polar Surface Area
868.37	5.67	5.67
854.34	5.28	5.28

Parent Molecular Weight

ALogP

Polar Surface Area

868.37

5.67

854.34

5.28

Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as increase in ratio of LC3B2 to LC3B1 at 30 to 300 nM measured afte...

Basic Information

Activity Charts

Compound Summary